Multiple squamous cell carcinomas in head and neck and esophagus.

Бүгдэнд нь энэ өдрийн мэнд!

Саяхан бидэнд улаан хоолой, төвөнхийн давхар анхдагч (double primary) хавтгай хучуур эдийн хавдрын сонирхолтой тохиолдол ирснийг та бүхэнтэй хуваалцахыг хүслээ.

Өвчтөн 50 настай, эрэгтэй. Дурангийн биопси болон дүрс оношлогооны шинжилгээгээр улаан хоолой, төвөнхийн хавдартай болох нь оношлогдсон. Төвөнх, улаан хоолой тайрах, хүзүүний тунгалгийн булчирхай түүх хагалгаанууд хийгдсэн.

Gross findings of the esophagus.

The specimen consists of a segment of esophagus and short segment of stomach. The specimen measures 8.5 cm in length of esophagus and 3.5 cm in the longest length of stomach . The external surface is slightly irregular in the mid part. On opening, the esophageal mucosa reveals a well-defined ulceroinfiltrative lesion, measuring 3.5 x 3.5 cm. It is located at 3.5 cm and 3.5 cm apart from the proximal and distal resection margins, respectively.
After applying Lugol solution, it reveals an ill-defined geographic unstained mucosa around mass. There is another unstained mucosal leison, 2 cm apart from the mass, measuring 2.2 x 1 cm, abutting the proximal margin.
On section, the cut surface of main mass shows a white-gray infiltrative tumor, which seems to be extending to the muscle layer.
Microscopic feature of the main mass.
Microscopic feature of the main mass.
Microscopic feature of separate Lugol solution unstained area abutting the proximal margin.

Gross finding of the larynx.
The mucosal surface of the epiglottis area shows a gray white granular ulcerative lesion in the left side, measuring 2.5 x 2.5 x 1.7 cm. The mucosal resection margin of tongue base is grossly free from the tumor. On multiple cut sections, the tumor is gray white infiltrative tumor, which seems to be confined to the epiglottis.
Cut surface and microscopic finding of main glottic tumor.

Gross and microscopic finding of mucosal irregularity in right subglottic area.